VIP (Vasoactive Intestinal Peptide)
ResearchA naturally occurring neuropeptide with powerful anti-inflammatory and immune-modulating properties. Researched for CIRS, autoimmune conditions, and gut health.
Immune SupportGut HealthAnti-Inflammatory
Half Life
~1-2 minutes
Time to Results
Weeks
Administration
Nasal spray, IV

๐พ Griffin's Research Scorecard
Research Strength
Human Data
Animal Data
Long-Term Data
Beginner Friendly
Storage Difficulty
Injection FrequencyMultiple times daily (nasal)
Cost$$$

๐พ Griffin Says...
VIP is particularly interesting for the CIRS (Chronic Inflammatory Response Syndrome) community. It's become a focus of researchers working on mold illness and chronic inflammation. The breadth of its anti-inflammatory action across multiple systems is remarkable.
Benefits
- Powerful anti-inflammatory
- Immune regulation
- Gut motility support
- CIRS research
- Lung function support
- Neuroprotection
Best For
- Chronic inflammation research
- CIRS research
- Autoimmune research
- Gut health
Body Systems
ImmuneGastrointestinalNervous SystemCardiovascular
Mechanisms of Action
- Binds VPAC1 and VPAC2 receptors
- Inhibits pro-inflammatory cytokines
- Promotes anti-inflammatory cytokines
- Vasodilatory effects
Side Effects
| Effect | Frequency | Severity |
|---|---|---|
| Facial flushing | Common (nasal) | Mild |
| Nausea | Uncommon | Mild |
| Elevated lipase (monitor) | Uncommon | Moderate |
Contraindications
Monitor lipase levels, caution with vasodilatory cardiovascular conditions
Peptides discussed here are for research purposes only. Nothing on this page is medical advice. Always consult a qualified professional before making health decisions.
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