SS-31 (Elamipretide)

FDA Approved

A mitochondria-targeting peptide that reduces oxidative stress and improves mitochondrial function. FDA approved for Barth syndrome. Researched for heart failure, aging, and energy.

LongevityCardiovascularEnergy & PerformanceMitochondrial Health

Half Life

~2 hours

Time to Results

Weeks to months

Administration

SubQ injection, IV

Griffin the guinea pig research guide

๐Ÿพ Griffin's Research Scorecard

Research Strength
Human Data
Animal Data
Long-Term Data
Beginner Friendly
Storage Difficulty
Injection FrequencyDaily
Cost$$$

๐Ÿพ Griffin Says...

FDA approved for Barth syndrome in 2025, making it one of the newest additions to the approved list. The mitochondrial targeting mechanism is unique and fascinating. Strong scientific basis for cardiovascular and aging research.

Benefits

  • Mitochondrial function improvement
  • Reduced oxidative stress
  • Cardiovascular support
  • Energy production
  • Anti-aging potential

Best For

  • Mitochondrial health research
  • Cardiovascular research
  • Anti-aging
  • Energy research

Body Systems

CardiovascularCellularMetabolic

Mechanisms of Action

  • Targets cardiolipin in inner mitochondrial membrane
  • Reduces reactive oxygen species
  • Improves electron transport chain efficiency
  • Protects mitochondrial function

Side Effects

EffectFrequencySeverity
Injection site reactionsCommonMild
Fatigue initiallyUncommonMild

Contraindications

None well established outside of indicated conditions

Peptides discussed here are for research purposes only. Nothing on this page is medical advice. Always consult a qualified professional before making health decisions.

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