PT-141
FDA ApprovedAlso known as Bremelanotide, PT-141 is an FDA-approved peptide for sexual dysfunction. It works centrally in the brain rather than on the vascular system like traditional treatments.
Sexual HealthReproductive Health
Half Life
~2.7 hours
Time to Results
Within hours of dosing
Administration
SubQ injection, Nasal spray

๐พ Griffin's Research Scorecard
Research Strength
Human Data
Animal Data
Long-Term Data
Beginner Friendly
Storage Difficulty
Injection FrequencyAs needed (not daily)
Cost$$$

๐พ Griffin Says...
FDA approved for HSDD (hypoactive sexual desire disorder) in premenopausal women. Also researched for men who don't respond to Viagra. Works differently from other sexual health treatments since it acts on the brain, not blood vessels.
Benefits
- Increased libido
- Sexual arousal
- Improved erectile function
- Works for both men and women
- Alternative for those unresponsive to PDE5 inhibitors
Best For
- Sexual health research
- Libido research
Body Systems
Nervous SystemReproductiveEndocrine
Mechanisms of Action
- Melanocortin 4 receptor agonist
- Acts centrally in brain to stimulate sexual desire
- Does not affect vascular system directly
Side Effects
| Effect | Frequency | Severity |
|---|---|---|
| Nausea | Common | Mild |
| Facial flushing | Common | Mild |
| Headache | Common | Mild |
| Temporary blood pressure changes | Uncommon | Moderate |
Contraindications
Cardiovascular disease, high blood pressure, pregnancy, combined with cardiovascular drugs
Peptides discussed here are for research purposes only. Nothing on this page is medical advice. Always consult a qualified professional before making health decisions.
Ready to calculate your dose? Use Griffin's Peptide Calculator ๐พ
Open Calculator