MK-677
ResearchAn oral growth hormone secretagogue (technically a small molecule, not a peptide). Researched for GH and IGF-1 elevation, muscle mass, sleep quality, and bone density.
Growth HormoneBody CompositionSleep
Half Life
~24 hours
Time to Results
4-8 weeks
Administration
Oral
🐾 Griffin's Research Scorecard
Research Strength
Human Data
Animal Data
Long-Term Data
Beginner Friendly
Storage Difficulty
Injection FrequencyDaily (oral)
Cost$$$
🐾 Griffin Says...
The oral option for GH research, which lowers the barrier to entry significantly. No injections needed. Downside is it raises blood sugar and has significant appetite effects. Worth monitoring glucose levels during research.
Benefits
- Oral GH stimulation
- IGF-1 increase
- Muscle mass support
- Improved deep sleep
- Bone density research
- Appetite stimulation
Best For
- GH research without injections
- Body composition
- Sleep research
- Bone health
Body Systems
EndocrineMusculoskeletalNervous System
Mechanisms of Action
- Ghrelin receptor agonist
- Oral bioavailability
- Stimulates pituitary GH release
- Long half-life for sustained effect
Side Effects
| Effect | Frequency | Severity |
|---|---|---|
| Increased appetite | Very Common | Mild |
| Water retention | Common | Mild |
| Elevated fasting glucose | Common | Moderate |
| Lethargy at first | Uncommon | Mild |
Contraindications
Diabetes or pre-diabetes (raises blood sugar), active cancer
Peptides discussed here are for research purposes only. Nothing on this page is medical advice. Always consult a qualified professional before making health decisions.
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