The classic GH optimization stack. CJC-1295 triggers GH release while Ipamorelin amplifies it - together creating synergistic and sustained GH elevation.
Role: Supports muscle
Full peptide profile All stacksMuscle 
The Classic GH Muscle Stack
CJC-1295 is a GHRH analog — it works like the signal your hypothalamus sends to your pituitary to prepare for GH release. Ipamorelin is a GHRP — it works like ghrelin, the signal that actually pulls the trigger on GH secretion. When you combine a GHRH with a GHRP, you get synergistic GH release that is significantly higher than either compound alone. Research suggests the combination increases GH output by 200-300% compared to baseline. Because Ipamorelin is selective (does not raise cortisol or prolactin like other GHRPs), it is considered the cleanest option for this stack. GH pulses triggered before bed align with the natural GH release that occurs during deep sleep — the time when muscle repair and growth is highest.
🐾 Griffin Says...
This is the starter muscle stack for a reason. Clean, well-researched, synergistic. CJC-1295 primes the pituitary and Ipamorelin pulls the trigger. The timing before bed matters — you are layering on top of your body's natural GH pulse. One of the first stacks Griffin points beginners toward for body composition research.
Peptides in this stack
A long-acting growth hormone releasing hormone analog, often paired with Ipamorelin.
Role: Supports muscle
Full peptide profileA selective growth hormone secretagogue known for a clean side-effect profile.
Role: Supports muscle
Full peptide profileFor research purposes only. Nothing on this page is medical advice or a recommendation to use these compounds. Always consult a qualified professional before making health decisions.
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