An FDA-approved GHRH analog specifically approved for reducing excess abdominal fat in HIV patients with lipodystrophy. One of the strongest fat-targeting GH peptides.
Role: Supports fat loss
Full peptide profile All stacksFat Loss 
The Body Recomposition Stack
Tesamorelin is one of the only FDA-approved peptides specifically approved for abdominal fat reduction. It stimulates GH release from the pituitary, and GH has a well-documented effect on reducing visceral fat — the dangerous fat stored around internal organs. MOTS-c works at the mitochondrial level, activating the AMPK pathway (the same pathway triggered by exercise and caloric restriction) to improve insulin sensitivity and fat burning efficiency. Together they attack fat loss through hormonal signaling (Tesamorelin via GH) and cellular metabolism (MOTS-c via AMPK). This stack is particularly interesting for metabolic health research beyond simple weight loss.
🐾 Griffin Says...
Tesamorelin has real FDA approval data behind its fat reduction claims, which is notable. MOTS-c is newer and more experimental but the AMPK activation pathway is scientifically well-understood. This stack is particularly interesting for researchers focused on metabolic health rather than just the number on the scale.
Peptides in this stack
A mitochondria-derived peptide that regulates metabolism at the cellular level. Researched for insulin sensitivity, fat regulation, exercise performance, and longevity.
Role: Supports fat loss
Full peptide profileFor research purposes only. Nothing on this page is medical advice or a recommendation to use these compounds. Always consult a qualified professional before making health decisions.
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